EOG803073 GO:0004842 28/103 ubiquitin-protein transferase activity molecular_function "Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages." [GOC:BioGRID, GOC:jh2, PMID:9635407] EOG803073 GO:0023051 27/103 regulation of signaling biological_process "Any process that modulates the frequency, rate or extent of a signaling process." [GOC:mtg_signal] EOG803073 GO:0008270 23/103 zinc ion binding molecular_function "Interacting selectively and non-covalently with zinc (Zn) ions." [GOC:ai] EOG803073 GO:0005509 23/103 calcium ion binding molecular_function "Interacting selectively and non-covalently with calcium ions (Ca2+)." [GOC:ai] EOG803073 GO:0005634 19/103 nucleus cellular_component "A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent." [GOC:go_curators] EOG803073 GO:0004871 19/103 signal transducer activity molecular_function "Conveys a signal across a cell to trigger a change in cell function or state. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response." [GOC:go_curators] EOG803073 GO:0007166 18/103 cell surface receptor signaling pathway biological_process "A series of molecular signals initiated by activation of a receptor on the surface of a cell. The pathway begins with binding of an extracellular ligand to a cell surface receptor, or for receptors that signal in the absence of a ligand, by ligand-withdrawal or the activity of a constitutively active receptor. The pathway ends with regulation of a downstream cellular process, e.g. transcription." [GOC:bf, GOC:mah, GOC:pr, GOC:signaling] EOG803073 GO:0048134 1/103 germ-line cyst formation biological_process "Formation of a group of interconnected cells derived from a single gonial founder cell." [GOC:jid, PMID:10370240, PMID:21681920] EOG803073 GO:0030971 1/103 receptor tyrosine kinase binding molecular_function "Interacting selectively and non-covalently with a receptor that possesses protein tyrosine kinase activity." [GOC:mah] EOG803073 GO:0009950 1/103 dorsal/ventral axis specification biological_process "The establishment, maintenance and elaboration of the dorsal/ventral axis. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism." [GOC:dph, GOC:go_curators, GOC:tb] EOG803073 GO:0016874 1/103 ligase activity molecular_function "Catalysis of the joining of two substances, or two groups within a single molecule, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate." [EC:6, GOC:mah] EOG803073 GO:0001784 1/103 phosphotyrosine binding molecular_function "Interacting selectively and non-covalently with a phosphorylated tyrosine residue within a protein." [PMID:14636584] EOG803073 GO:0007465 1/103 R7 cell fate commitment biological_process "The process in which the R7 photoreceptor commits to its cell fate. The R7 receptor contributes the central part of the rhabdomere in the apical parts of the ommatidium." [PMID:3076112, PMID:3937883] EOG803073 GO:0006508 1/103 proteolysis biological_process "The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds." [GOC:bf, GOC:mah] EOG803073 GO:0005938 1/103 cell cortex cellular_component "The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins." [GOC:mah, ISBN:0815316194] EOG803073 GO:0008340 1/103 determination of adult lifespan biological_process "The control of viability and duration in the adult phase of the life-cycle." [GOC:ems] EOG803073 GO:0042127 1/103 regulation of cell proliferation biological_process "Any process that modulates the frequency, rate or extent of cell proliferation." [GOC:jl] EOG803073 GO:0006897 1/103 endocytosis biological_process "A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle." [GOC:mah, ISBN:0198506732, ISBN:0716731363] EOG803073 GO:0010941 1/103 regulation of cell death biological_process "Any process that modulates the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death." [GOC:dph, GOC:tb] EOG803073 GO:0033500 1/103 carbohydrate homeostasis biological_process "A homeostatic process involved in the maintenance of an internal steady state of a carbohydrate within an organism or cell." [GOC:mah] EOG803073 GO:0005515 1/103 protein binding molecular_function "Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules)." [GOC:go_curators] EOG803073 GO:0008069 1/103 dorsal/ventral axis specification, ovarian follicular epithelium biological_process "Polarization of the ovarian follicle cells along the dorsal/ventral axis. An example of this process is found in Drosophila melanogaster." [GOC:bf, GOC:dph, GOC:mtg_sensu, GOC:tb] EOG803073 GO:0042059 1/103 negative regulation of epidermal growth factor receptor signaling pathway biological_process "Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity." [GOC:go_curators] EOG803073 GO:0007476 1/103 imaginal disc-derived wing morphogenesis biological_process "The process in which the anatomical structures of the imaginal disc-derived wing are generated and organized. The wing is an appendage modified for flying." [GOC:bf, GOC:mtg_sensu] EOG803073 GO:0007175 1/103 negative regulation of epidermal growth factor-activated receptor activity biological_process "Any process that stops, prevents, or reduces the frequency, rate or extent of EGF-activated receptor activity." [GOC:go_curators] EOG803073 GO:0005737 1/103 cytoplasm cellular_component "All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures." [ISBN:0198547684] EOG803073 GO:0007298 1/103 border follicle cell migration biological_process "The directed movement of a border cell through the nurse cells to reach the oocyte. An example of this is found in Drosophila melanogaster." [GOC:mtg_sensu, PMID:10822261] EOG803073 GO:0007173 1/103 epidermal growth factor receptor signaling pathway biological_process "A series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor EGFR (ERBB1) on the surface of a cell. The pathway ends with regulation of a downstream cellular process, e.g. transcription." [GOC:ceb, PR:000006933] EOG803073 GO:0001754 1/103 eye photoreceptor cell differentiation biological_process "The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell, as found in the eye, the primary visual organ of most organisms." [GOC:go_curators]