EOG82VBWR GO:0004707 24/98 MAP kinase activity molecular_function "Catalysis of the reaction: protein + ATP = protein phosphate + ADP. This reaction is the phosphorylation of proteins. Mitogen-activated protein kinase; a family of protein kinases that perform a crucial step in relaying signals from the plasma membrane to the nucleus. They are activated by a wide range of proliferation- or differentiation-inducing signals; activation is strong with agonists such as polypeptide growth factors and tumor-promoting phorbol esters, but weak (in most cell backgrounds) by stress stimuli." [GOC:ma, ISBN:0198547684] EOG82VBWR GO:0005524 24/98 ATP binding molecular_function "Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator." [ISBN:0198506732] EOG82VBWR GO:0034614 1/98 cellular response to reactive oxygen species biological_process "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals." [GOC:mah] EOG82VBWR GO:0045467 1/98 R7 cell development biological_process "The process whose specific outcome is the progression of the R7 photoreceptor over time, from its formation to the mature structure. The R7 photoreceptor is the last photoreceptor to develop in the ommatidium." [PMID:11880339] EOG82VBWR GO:0008595 1/98 anterior/posterior axis specification, embryo biological_process "The specification of the anterior/posterior axis of the embryo by the products of genes expressed maternally and genes expressed in the zygote." [http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm, ISBN:0879694238] EOG82VBWR GO:0005737 1/98 cytoplasm cellular_component "All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures." [ISBN:0198547684] EOG82VBWR GO:0048149 1/98 behavioral response to ethanol biological_process "Any process that results in a change in the behavior of an organism as a result of an ethanol stimulus." [GOC:jid] EOG82VBWR GO:0071276 1/98 cellular response to cadmium ion biological_process "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus." [GOC:mah] EOG82VBWR GO:0019901 1/98 protein kinase binding molecular_function "Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate." [GOC:jl] EOG82VBWR GO:0030054 1/98 cell junction cellular_component "A cellular component that forms a specialized region of connection between two or more cells or between a cell and the extracellular matrix. At a cell junction, anchoring proteins extend through the plasma membrane to link cytoskeletal proteins in one cell to cytoskeletal proteins in neighboring cells or to proteins in the extracellular matrix." [GOC:mah, http://www.vivo.colostate.edu/hbooks/cmb/cells/pmemb/junctions_a.html, ISBN:0198506732] EOG82VBWR GO:0090303 1/98 positive regulation of wound healing biological_process "Any process that increases the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury." [GOC:BHF] EOG82VBWR GO:0008134 1/98 transcription factor binding molecular_function "Interacting selectively and non-covalently with a transcription factor, any protein required to initiate or regulate transcription." [ISBN:0198506732] EOG82VBWR GO:0005634 1/98 nucleus cellular_component "A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent." [GOC:go_curators] EOG82VBWR GO:2001023 1/98 regulation of response to drug biological_process "Any process that modulates the frequency, rate or extent of response to drug." [GOC:obol] EOG82VBWR GO:0034334 1/98 adherens junction maintenance biological_process "The maintenance of an adherens junction. An adherens junction is a cell junction at which the cytoplasmic face of the plasma membrane is attached to actin filaments." [GOC:mah] EOG82VBWR GO:0004674 1/98 protein serine/threonine kinase activity molecular_function "Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate." [GOC:bf] EOG82VBWR GO:0007258 1/98 JUN phosphorylation biological_process "The process of introducing a phosphate group into a JUN protein." [GOC:jl] EOG82VBWR GO:0043066 1/98 negative regulation of apoptotic process biological_process "Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process." [GOC:jl, GOC:mtg_apoptosis] EOG82VBWR GO:0006355 1/98 regulation of transcription, DNA-templated biological_process "Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription." [GOC:go_curators, GOC:txnOH] EOG82VBWR GO:0007067 1/98 mitotic nuclear division biological_process "A cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell." [GOC:dph, GOC:ma, GOC:mah, ISBN:0198547684] EOG82VBWR GO:0007552 1/98 metamorphosis biological_process "A biological process in which an animal physically develops after birth or hatching, involving a conspicuous and relatively abrupt change in the animal's form or structure. Examples include the change from tadpole to frog, and the change from larva to adult. An example of this is found in Drosophila melanogaster." [GOC:sensu, ISBN:0198506732, ISBN:0721662544] EOG82VBWR GO:0007474 1/98 imaginal disc-derived wing vein specification biological_process "The regionalization process in which the area of a imaginal disc-derived wing that will form a wing vein is specified." [GOC:dph, GOC:isa_complete, GOC:mtg_sensu] EOG82VBWR GO:0000165 1/98 MAPK cascade biological_process "An intracellular protein kinase cascade containing at least a MAPK, a MAPKK and a MAP3K. The cascade can also contain two additional tiers: the upstream MAP4K and the downstream MAP Kinase-activated kinase (MAPKAPK). The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell." [GOC:bf, GOC:mtg_signaling_feb11, PMID:20811974, PMID:9561267] EOG82VBWR GO:0008293 1/98 torso signaling pathway biological_process "A series of molecular signals initiated by the binding of an extracellular ligand to torso (a receptor tyrosine kinase) on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:go_curators, PMID:8343949] EOG82VBWR GO:0046534 1/98 positive regulation of photoreceptor cell differentiation biological_process "Any process that activates or increases the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster." [GOC:go_curators] EOG82VBWR GO:0008586 1/98 imaginal disc-derived wing vein morphogenesis biological_process "The process in which anatomical structures of the veins on an imaginal disc-derived wing are generated and organized." [GOC:mtg_sensu] EOG82VBWR GO:0006974 1/98 cellular response to DNA damage stimulus biological_process "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism." [GOC:go_curators] EOG82VBWR GO:0071243 1/98 cellular response to arsenic-containing substance biological_process "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides." [GOC:mah] EOG82VBWR GO:0004705 1/98 JUN kinase activity molecular_function "Catalysis of the reaction: JUN + ATP = JUN phosphate + ADP. This reaction is the phosphorylation and activation of members of the JUN family, a gene family that encodes nuclear transcription factors." [GOC:bf, ISBN:0198506732] EOG82VBWR GO:0007507 1/98 heart development biological_process "The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood." [GOC:jid, UBERON:0000948] EOG82VBWR GO:0007476 1/98 imaginal disc-derived wing morphogenesis biological_process "The process in which the anatomical structures of the imaginal disc-derived wing are generated and organized. The wing is an appendage modified for flying." [GOC:bf, GOC:mtg_sensu] EOG82VBWR GO:0009267 1/98 cellular response to starvation biological_process "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment." [GOC:jl] EOG82VBWR GO:0008284 1/98 positive regulation of cell proliferation biological_process "Any process that activates or increases the rate or extent of cell proliferation." [GOC:go_curators] EOG82VBWR GO:0007169 1/98 transmembrane receptor protein tyrosine kinase signaling pathway biological_process "A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell where the receptor possesses tyrosine kinase activity, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:ceb, GOC:signaling] EOG82VBWR GO:0050804 1/98 modulation of synaptic transmission biological_process "Any process that modulates the frequency or rate of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse." [GOC:ai] EOG82VBWR GO:0006468 1/98 protein phosphorylation biological_process "The process of introducing a phosphate group on to a protein." [GOC:hb] EOG82VBWR GO:0016242 1/98 negative regulation of macroautophagy biological_process "Any process that stops, prevents, or reduces the frequency, rate or extent of macroautophagy." [GOC:go_curators] EOG82VBWR GO:0005515 1/98 protein binding molecular_function "Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules)." [GOC:go_curators] EOG82VBWR GO:0007369 1/98 gastrulation biological_process "A complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. The details of gastrulation vary from species to species, but usually result in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm." [GOC:curators, ISBN:9780878933846] EOG82VBWR GO:0050803 1/98 regulation of synapse structure or activity biological_process "Any process that modulates the physical form or the activity of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell)." [GOC:ai]