EOG8323C8 GO:0016021 40/126 integral component of membrane cellular_component "The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:dos, GOC:go_curators] EOG8323C8 GO:0004994 31/126 somatostatin receptor activity molecular_function "Combining with somatostatin to initiate a change in cell activity. Somatostatin is a peptide hormone that regulates the endocrine system by signaling via G-protein coupled somatostatin receptors. Somatostatin has two active forms produced by proteolytic cleavage: a 14 amino acid peptide (SST-14) and a 28 amino acid peptide (SST-28)." [GOC:ai, GOC:bf, Wikipedia:Somatostatin] EOG8323C8 GO:0004985 5/126 opioid receptor activity molecular_function "Combining with an opioid (any narcotic derived from or resembling opium), and transmitting the signal across the membrane by activating an associated G-protein." [CHEBI:60598, GOC:ai, GOC:bf, PMID:20494127] EOG8323C8 GO:0004930 3/126 G-protein coupled receptor activity molecular_function "Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex." [GOC:bf, http://www.iuphar-db.org, Wikipedia:GPCR] EOG8323C8 GO:0005887 2/126 integral component of plasma membrane cellular_component "The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:dos, GOC:go_curators] EOG8323C8 GO:0050254 2/126 rhodopsin kinase activity molecular_function "Catalysis of the reaction: ATP + rhodopsin = ADP + phosphorhodopsin." [EC:2.7.11.14, MetaCyc:RHODOPSIN-KINASE-RXN] EOG8323C8 GO:0007218 2/126 neuropeptide signaling pathway biological_process "The series of molecular signals generated as a consequence of a peptide neurotransmitter binding to a cell surface receptor." [GOC:mah, ISBN:0815316194] EOG8323C8 GO:0007186 2/126 G-protein coupled receptor signaling pathway biological_process "A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane (PMID:24568158 and PMID:16902576)." [GOC:bf, GOC:mah, PMID:16902576PMID\:24568158, Wikipedia:G_protein-coupled_receptor] EOG8323C8 GO:0008188 2/126 neuropeptide receptor activity molecular_function "Combining with a neuropeptide to initiate a change in cell activity." [GOC:ai] EOG8323C8 GO:0008261 2/126 allatostatin receptor activity molecular_function "Combining with allatostatin to initiate a change in cell activity." [GOC:ai] EOG8323C8 GO:0004983 1/126 neuropeptide Y receptor activity molecular_function "Combining with neuropeptide Y to initiate a change in cell activity." [PMID:9315606]