EOG837TV7 GO:0007165 24/89 signal transduction biological_process "The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell." [GOC:go_curators, GOC:mtg_signaling_feb11] EOG837TV7 GO:0046872 23/89 metal ion binding molecular_function "Interacting selectively and non-covalently with any metal ion." [GOC:ai] EOG837TV7 GO:0004114 23/89 3',5'-cyclic-nucleotide phosphodiesterase activity molecular_function "Catalysis of the reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate." [EC:3.1.4.17] EOG837TV7 GO:0005615 1/89 extracellular space cellular_component "That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid." [ISBN:0198547684] EOG837TV7 GO:0046058 1/89 cAMP metabolic process biological_process "The chemical reactions and pathways involving the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate)." [GOC:go_curators] EOG837TV7 GO:0048101 1/89 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity molecular_function "Catalysis of the reaction: guanosine 3',5'-cyclic phosphate + H2O = guanosine 5'-phosphate. The reaction is calmodulin and calcium-sensitive." [GOC:jid] EOG837TV7 GO:0032504 1/89 multicellular organism reproduction biological_process "The biological process in which new individuals are produced by one or two multicellular organisms. The new individuals inherit some proportion of their genetic material from the parent or parents." [GOC:isa_complete, GOC:jid] EOG837TV7 GO:0060179 1/89 male mating behavior biological_process "The specific behavior of a male organism that is associated with reproduction." [GOC:dph, GOC:pr, GOC:tb] EOG837TV7 GO:0047555 1/89 3',5'-cyclic-GMP phosphodiesterase activity molecular_function "Catalysis of the reaction: guanosine 3',5'-cyclic phosphate + H2O = guanosine 5'-phosphate." [EC:3.1.4.35, MetaCyc:35-CYCLIC-GMP-PHOSPHODIESTERASE-RXN] EOG837TV7 GO:0004115 1/89 3',5'-cyclic-AMP phosphodiesterase activity molecular_function "Catalysis of the reaction: adenosine 3',5'-cyclic phosphate + H2O = adenosine 5'-phosphate." [GOC:ai] EOG837TV7 GO:0046068 1/89 cGMP metabolic process biological_process "The chemical reactions and pathways involving cyclic GMP, guanosine 3',5'-phosphate." [GOC:go_curators] EOG837TV7 GO:0005516 1/89 calmodulin binding molecular_function "Interacting selectively and non-covalently with calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states." [GOC:krc]