EOG83JFJQ GO:0015031 2/86 protein transport biological_process "The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] EOG83JFJQ GO:0005768 1/86 endosome cellular_component "A membrane-bounded organelle to which materials ingested by endocytosis are delivered." [ISBN:0198506732, PMID:19696797] EOG83JFJQ GO:0005794 1/86 Golgi apparatus cellular_component "A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions." [ISBN:0198506732] EOG83JFJQ GO:0031532 1/86 actin cytoskeleton reorganization biological_process "A process that is carried out at the cellular level which results in dynamic structural changes to the arrangement of constituent parts of cytoskeletal structures comprising actin filaments and their associated proteins." [GOC:ecd, GOC:mah] EOG83JFJQ GO:0005086 1/86 ARF guanyl-nucleotide exchange factor activity molecular_function "Stimulates the exchange of guanyl nucleotides associated with the GTPase ARF. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase." [GOC:mah] EOG83JFJQ GO:0005519 1/86 cytoskeletal regulatory protein binding molecular_function "Interacting selectively and non-covalently with any protein involved in modulating the reorganization of the cytoskeleton." [GOC:go_curators, PMID:15163540] EOG83JFJQ GO:0016192 1/86 vesicle-mediated transport biological_process "A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane." [GOC:ai, GOC:mah, ISBN:08789310662000] EOG83JFJQ GO:0043087 1/86 regulation of GTPase activity biological_process "Any process that modulates the rate of GTP hydrolysis by a GTPase." [GOC:jl, GOC:mah] EOG83JFJQ GO:0005802 1/86 trans-Golgi network cellular_component "The network of interconnected tubular and cisternal structures located within the Golgi apparatus on the side distal to the endoplasmic reticulum, from which secretory vesicles emerge. The trans-Golgi network is important in the later stages of protein secretion where it is thought to play a key role in the sorting and targeting of secreted proteins to the correct destination." [GOC:vw, ISBN:0815316194] EOG83JFJQ GO:0007318 1/86 pole plasm protein localization biological_process "Any process in which a protein is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster." [GOC:ai]