EOG847J7P GO:0005737 1/90 cytoplasm cellular_component "All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures." [ISBN:0198547684] EOG847J7P GO:0000338 1/90 protein deneddylation biological_process "The removal of a ubiquitin-like protein of the NEDD8 type from a protein." [GOC:krc] EOG847J7P GO:0019781 1/90 NEDD8 activating enzyme activity molecular_function "Catalysis of the initiation of the NEDD8 (RUB1) conjugation cascade." [PMID:12646924] EOG847J7P GO:0005515 1/90 protein binding molecular_function "Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules)." [GOC:go_curators] EOG847J7P GO:0007095 1/90 mitotic G2 DNA damage checkpoint biological_process "A mitotic cell cycle checkpoint that detects and negatively regulates progression through the G2/M transition of the cell cycle in response to DNA damage." [GOC:mtg_cell_cycle] EOG847J7P GO:0001751 1/90 compound eye photoreceptor cell differentiation biological_process "The process in which a relatively unspecialized cell acquires the specialized features of an eye photoreceptor cell." [GOC:go_curators] EOG847J7P GO:0008180 1/90 COP9 signalosome cellular_component "A protein complex that catalyzes the deneddylation of proteins, including the cullin component of SCF ubiquitin E3 ligase; deneddylation increases the activity of cullin family ubiquitin ligases. The signalosome is involved in many regulatory process, including some which control development, in many species; also regulates photomorphogenesis in plants; in many species its subunits are highly similar to those of the proteasome." [PMID:11019806, PMID:12186635, PMID:14570571] EOG847J7P GO:0050821 1/90 protein stabilization biological_process "Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation." [GOC:ai] EOG847J7P GO:0032435 1/90 negative regulation of proteasomal ubiquitin-dependent protein catabolic process biological_process "Any process that stops, prevents, or reduces the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome." [GOC:mah] EOG847J7P GO:0044212 1/90 transcription regulatory region DNA binding molecular_function "Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors." [GOC:jl, GOC:txnOH, SO:0005836] EOG847J7P GO:0046331 1/90 lateral inhibition biological_process "Signaling between cells of equivalent developmental potential that results in these cells adopting different developmental fates. An example is the suppression by cells with a particular fate of the adoption of the same fate by surrounding cells." [GOC:bf, GOC:kmv] EOG847J7P GO:0048477 1/90 oogenesis biological_process "The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster." [GOC:kmv, GOC:mtg_sensu, GOC:pr]