EOG8G7FD0 GO:0030429 8/14 kynureninase activity molecular_function "Catalysis of the reaction: L-kynurenine + H2O = anthranilate + L-alanine." [EC:3.7.1.3] EOG8G7FD0 GO:0030170 8/14 pyridoxal phosphate binding molecular_function "Interacting selectively and non-covalently with pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6." [GOC:mah, ISBN:0198506732] EOG8G7FD0 GO:0005737 8/14 cytoplasm cellular_component "All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures." [ISBN:0198547684] EOG8G7FD0 GO:0006569 8/14 tryptophan catabolic process biological_process "The chemical reactions and pathways resulting in the breakdown of tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid." [ISBN:0198547684] EOG8G7FD0 GO:0034354 5/14 'de novo' NAD biosynthetic process from tryptophan biological_process "The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD), beginning with the synthesis of tryptophan from simpler precursors; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH." [PMID:17161604] EOG8G7FD0 GO:0043420 5/14 anthranilate metabolic process biological_process "The chemical reactions and pathways involving anthranilate (2-aminobenzoate)." [CHEBI:16567, GOC:jl] EOG8G7FD0 GO:0019805 5/14 quinolinate biosynthetic process biological_process "The chemical reactions and pathways resulting in the formation of quinolinate, the anion of quinolinic acid, also known as 2,3-pyridinedicarboxylic acid." [GOC:ai] EOG8G7FD0 GO:0097053 5/14 L-kynurenine catabolic process biological_process "The chemical reactions and pathways resulting in the breakdown of L-kynurenine, the L-enantiomer of the amino acid kynurenine (3-(2-aminobenzoyl)-alanine)." [CHEBI:16946, GOC:yaf] EOG8G7FD0 GO:0009435 3/14 NAD biosynthetic process biological_process "The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide, a coenzyme present in most living cells and derived from the B vitamin nicotinic acid; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH." [GOC:jl, ISBN:0618254153]