EOG8GQSJW GO:0005615 39/119 extracellular space cellular_component "That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid." [ISBN:0198547684] EOG8GQSJW GO:0008233 5/119 peptidase activity molecular_function "Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid." [GOC:jl, ISBN:0815332181] EOG8GQSJW GO:0016740 5/119 transferase activity molecular_function "Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2." [ISBN:0198506732] EOG8GQSJW GO:0048149 1/119 behavioral response to ethanol biological_process "Any process that results in a change in the behavior of an organism as a result of an ethanol stimulus." [GOC:jid] EOG8GQSJW GO:0035011 1/119 melanotic encapsulation of foreign target biological_process "Formation of a multilayered, melanized sheath of cells around a foreign invader." [GOC:bf] EOG8GQSJW GO:0009611 1/119 response to wounding biological_process "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism." [GOC:go_curators] EOG8GQSJW GO:0008063 1/119 Toll signaling pathway biological_process "A series of molecular signals initiated by the binding of an extracellular ligand to the receptor Toll on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:go_curators, PMID:11135568, PMID:19126860] EOG8GQSJW GO:0005576 1/119 extracellular region cellular_component "The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite." [GOC:go_curators] EOG8GQSJW GO:0010951 1/119 negative regulation of endopeptidase activity biological_process "Any process that decreases the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins." [GOC:dph, GOC:tb] EOG8GQSJW GO:0004857 1/119 enzyme inhibitor activity molecular_function "Binds to and stops, prevents or reduces the activity of an enzyme." [GOC:ai] EOG8GQSJW GO:0002213 1/119 defense response to insect biological_process "A response to protect an organism from a directly detected or perceived external threat from an insect or insects to that organism." [GOC:add] EOG8GQSJW GO:0000155 1/119 phosphorelay sensor kinase activity molecular_function "Catalysis of the phosphorylation of a histidine residue in response to detection of an extracellular signal such as a chemical ligand or change in environment, to initiate a change in cell state or activity. The two-component sensor is a histidine kinase that autophosphorylates a histidine residue in its active site. The phosphate is then transferred to an aspartate residue in a downstream response regulator, to trigger a response." [GOC:bf, GOC:mcc, PMID:10966457, PMID:20223701, PMID:9191038] EOG8GQSJW GO:0009950 1/119 dorsal/ventral axis specification biological_process "The establishment, maintenance and elaboration of the dorsal/ventral axis. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism." [GOC:dph, GOC:go_curators, GOC:tb] EOG8GQSJW GO:0045861 1/119 negative regulation of proteolysis biological_process "Any process that stops, prevents, or reduces the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein." [GOC:go_curators] EOG8GQSJW GO:0035006 1/119 melanization defense response biological_process "The blackening of the wounded area of the cuticle or the surface of invading pathogens, parasites or parasitoids, resulting from a proteolytic cascade leading to the de novo synthesis and deposition of melanin." [GOC:bf, PMID:12408809] EOG8GQSJW GO:0035009 1/119 negative regulation of melanization defense response biological_process "Any process that reduces the rate or extent of the melanization defense response. This regulation is critical to limit melanization to the site of injury or infection." [GOC:bf, PMID:12408809] EOG8GQSJW GO:0004867 1/119 serine-type endopeptidase inhibitor activity molecular_function "Stops, prevents or reduces the activity of serine-type endopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide bonds in a polypeptide chain; a serine residue (and a histidine residue) are at the active center of the enzyme." [GOC:ai] EOG8GQSJW GO:0016020 1/119 membrane cellular_component "A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it." [GOC:dos, GOC:mah, ISBN:0815316194] EOG8GQSJW GO:0050832 1/119 defense response to fungus biological_process "Reactions triggered in response to the presence of a fungus that act to protect the cell or organism." [GOC:ai]