EOG8K9DSN	GO:0005634	27/92	nucleus	cellular_component	"A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent." [GOC:go_curators]
EOG8K9DSN	GO:0005496	27/92	steroid binding	molecular_function	"Interacting selectively and non-covalently with a steroid, any of a large group of substances that have in common a ring system based on 1,2-cyclopentanoperhydrophenanthrene." [GOC:jl, ISBN:0198506732]
EOG8K9DSN	GO:0004884	27/92	ecdysteroid hormone receptor activity	molecular_function	"Combining with an ecdysteroid hormone and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II." [GOC:signaling, PMID:1653701]
EOG8K9DSN	GO:0008270	27/92	zinc ion binding	molecular_function	"Interacting selectively and non-covalently with zinc (Zn) ions." [GOC:ai]
EOG8K9DSN	GO:0043565	26/92	sequence-specific DNA binding	molecular_function	"Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding." [GOC:jl]
EOG8K9DSN	GO:0007552	1/92	metamorphosis	biological_process	"A biological process in which an animal physically develops after birth or hatching, involving a conspicuous and relatively abrupt change in the animal's form or structure. Examples include the change from tadpole to frog, and the change from larva to adult. An example of this is found in Drosophila melanogaster." [GOC:sensu, ISBN:0198506732, ISBN:0721662544]
EOG8K9DSN	GO:0070491	1/92	repressing transcription factor binding	molecular_function	"Interacting selectively and non-covalently with a transcription repressor, any protein whose activity is required to prevent or downregulate transcription." [GOC:mah, GOC:txnOH]
EOG8K9DSN	GO:0035180	1/92	larval wandering behavior	biological_process	"The movement of a third instar larva through a substrate in search of a pupation site. This movement occurs without feeding and is characterized by short bursts of forward movement, separated by stops and repeated side-to-side head probes, followed normally by a change in direction." [PMID:12848927, PMID:12956960]
EOG8K9DSN	GO:0007616	1/92	long-term memory	biological_process	"The memory process that deals with the storage, retrieval and modification of information a long time (typically weeks, months or years) after receiving that information. This type of memory is typically dependent on gene transcription regulated by second messenger activation." [http://hebb.mit.edu/courses/9.03/lecture4.html, ISBN:0582227089]
EOG8K9DSN	GO:0045892	1/92	negative regulation of transcription, DNA-templated	biological_process	"Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription." [GOC:go_curators, GOC:txnOH]
EOG8K9DSN	GO:0006911	1/92	phagocytosis, engulfment	biological_process	"The internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis, including the membrane and cytoskeletal processes required, which involves one of three mechanisms: zippering of pseudopods around a target via repeated receptor-ligand interactions, sinking of the target directly into plasma membrane of the phagocytosing cell, or induced uptake via an enhanced membrane ruffling of the phagocytosing cell similar to macropinocytosis." [GOC:curators, ISBN:0781735149]
EOG8K9DSN	GO:0035188	1/92	hatching	biological_process	"The emergence of an immature organism from a protective structure." [GOC:dgh, GOC:isa_complete, ISBN:0198612001]
EOG8K9DSN	GO:0044130	1/92	negative regulation of growth of symbiont in host	biological_process	"Any process in which the symbiont stops, prevents or reduces its increase in size or mass within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in the symbiotic interaction." [GOC:jl, GOC:pamgo_curators]
EOG8K9DSN	GO:0006914	1/92	autophagy	biological_process	"The process in which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation." [GOC:autophagy, ISBN:0198547684, PMID:11099404, PMID:9412464]
EOG8K9DSN	GO:0005737	1/92	cytoplasm	cellular_component	"All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures." [ISBN:0198547684]
EOG8K9DSN	GO:0018990	1/92	ecdysis, chitin-based cuticle	biological_process	"The shedding of the old chitin-based cuticlar fragments during the molting cycle. An example of this is found in Drosophila melanogaster." [GOC:bf, GOC:mtg_sensu]
EOG8K9DSN	GO:0035076	1/92	ecdysone receptor-mediated signaling pathway	biological_process	"The series of molecular signals generated by ecdysone binding to the ecdysone receptor complex." [GOC:bf]
EOG8K9DSN	GO:0010002	1/92	cardioblast differentiation	biological_process	"The process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating." [GOC:go_curators]
EOG8K9DSN	GO:0007298	1/92	border follicle cell migration	biological_process	"The directed movement of a border cell through the nurse cells to reach the oocyte. An example of this is found in Drosophila melanogaster." [GOC:mtg_sensu, PMID:10822261]
EOG8K9DSN	GO:0007488	1/92	histoblast morphogenesis	biological_process	"The process in which the anatomical structures derived from the histoblast disc are generated and organized. This includes the transformation of histoblast cells into adult structures during pupal metamorphosis. Histoblast cells are cells founded in the embryo that are the progenitors to the adult abdomen." [GOC:bf, ISBN:0879694238]
EOG8K9DSN	GO:0010506	1/92	regulation of autophagy	biological_process	"Any process that modulates the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm." [GOC:dph, GOC:tb]
EOG8K9DSN	GO:0001047	1/92	core promoter binding	molecular_function	"Interacting selectively and non-covalently with the regulatory region composed of the transcription start site and binding sites for the basal transcription machinery. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors." [GOC:txnOH]
EOG8K9DSN	GO:0007517	1/92	muscle organ development	biological_process	"The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work." [GOC:jid, ISBN:0198506732]
EOG8K9DSN	GO:0035297	1/92	regulation of Malpighian tubule diameter	biological_process	"Ensuring that the Malpighian tubule is the correct width. Malpighian tubules have a uniform circumference along their length; the circumference of the tubes is eight cells during the time the cells are dividing, after which the cells rearrange producting tubes with a cirumference of two cells." [PMID:9286684]
EOG8K9DSN	GO:0001225	1/92	RNA polymerase II transcription coactivator binding	molecular_function	"Interacting selectively and non-covalently with an RNA polymerase II transcription coactivator, any protein involved in positive regulation of transcription of RNA polymerase II via protein-protein interactions with transcription factors and other proteins that positively regulate transcription. Transcription coactivators do not bind DNA directly, but rather mediate protein-protein interactions between activating transcription factors and the basal transcription machinery of RNA polymerase II." [GOC:krc]
EOG8K9DSN	GO:0004879	1/92	RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding	molecular_function	"Combining with a signal and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II." [GOC:signaling, GOC:txnOH]
EOG8K9DSN	GO:0008340	1/92	determination of adult lifespan	biological_process	"The control of viability and duration in the adult phase of the life-cycle." [GOC:ems]
EOG8K9DSN	GO:0001077	1/92	transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	molecular_function	"Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) in order to activate or increase the frequency, rate or extent of transcription from the RNAP II promoter." [GOC:txnOH]
EOG8K9DSN	GO:0008362	1/92	chitin-based embryonic cuticle biosynthetic process	biological_process	"Synthesis, including the chemical reactions and pathways resulting in the formation of chitin and other components, and deposition of a chitin-based embryonic cuticle by the underlying epidermal epithelium. This tough, waterproof cuticle layer is essential to provide structural integrity of the larval body. An example of this is found in Drosophila melanogaster." [GOC:bf, GOC:mtg_sensu, PMID:12019232]
EOG8K9DSN	GO:0007390	1/92	germ-band shortening	biological_process	"The spreading of the amnioserosa from its compressed state to cover the whole of the dorsal surface. Initiating in the thorax and spreading posteriorly, it is accompanied by the transition from a parasegmental to segmental division of the embryo." [GOC:bf, PMID:12147138]
EOG8K9DSN	GO:0035073	1/92	pupariation	biological_process	"The onset of prepupal development when the larval stops crawling, everts its spiracles and the larval cuticle becomes the puparium or pupal case that surrounds the organism for the duration of metamorphosis." [GOC:bf, ISBN:0879694238, PMID:9409683]
EOG8K9DSN	GO:0005515	1/92	protein binding	molecular_function	"Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules)." [GOC:go_curators]
EOG8K9DSN	GO:0045944	1/92	positive regulation of transcription from RNA polymerase II promoter	biological_process	"Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:go_curators, GOC:txnOH]
EOG8K9DSN	GO:0030425	1/92	dendrite	cellular_component	"A neuron projection that has a short, tapering, often branched, morphology, receives and integrates signals from other neurons or from sensory stimuli, and conducts a nerve impulse towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body." [GOC:dos, GOC:mah, GOC:nln, ISBN:0198506732]
EOG8K9DSN	GO:0035053	1/92	dorsal vessel heart proper cell fate commitment	biological_process	"The commitment of dorsal vessel cardioblast cells to a heart proper cell fate and their capacity to differentiate into heart cells. An example of this process is found in Drosophila melanogaster." [GOC:bf, GOC:mtg_sensu, PMID:12397110]
EOG8K9DSN	GO:0007291	1/92	sperm individualization	biological_process	"The resolution of the male germline syncytium or cyst into individual gametes by packaging each spermatid into its own plasma membrane." [GOC:bf, PMID:9550716]
EOG8K9DSN	GO:0007409	1/92	axonogenesis	biological_process	"De novo generation of a long process of a neuron, that carries efferent (outgoing) action potentials from the cell body towards target cells. Refers to the morphogenesis or creation of shape or form of the developing axon." [GOC:dph, GOC:jid, GOC:pg, GOC:pr, ISBN:0198506732]
EOG8K9DSN	GO:0035206	1/92	regulation of hemocyte proliferation	biological_process	"Any process that modulates the frequency, rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this is found in Drosophila melanogaster." [GOC:bf, GOC:mtg_sensu]
EOG8K9DSN	GO:0007155	1/92	cell adhesion	biological_process	"The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules." [GOC:hb, GOC:pf]
EOG8K9DSN	GO:0035193	1/92	larval central nervous system remodeling	biological_process	"Reorganization of the pre-existing, functional larval central nervous system into one that can serve the novel behavioral needs of the adult. An example of this process is found in Drosophila melanogaster." [GOC:sensu, PMID:9647692]
EOG8K9DSN	GO:0000976	1/92	transcription regulatory region sequence-specific DNA binding	molecular_function	"Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon." [GOC:txnOH]
EOG8K9DSN	GO:0005700	1/92	polytene chromosome	cellular_component	"A type of chromosome in a polyploid cell, formed when multiple copies of homologous chromosomes are aligned side by side to give a giant chromosome in which distinct chromosome bands are readily visible." [ISBN:0198506732]
EOG8K9DSN	GO:0045893	1/92	positive regulation of transcription, DNA-templated	biological_process	"Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription." [GOC:go_curators, GOC:txnOH]
EOG8K9DSN	GO:0035072	1/92	ecdysone-mediated induction of salivary gland cell autophagic cell death	biological_process	"Any process induced by ecdysone that directly activates salivary gland programmed cell death during salivary gland histolysis." [GOC:bf]
EOG8K9DSN	GO:0048477	1/92	oogenesis	biological_process	"The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster." [GOC:kmv, GOC:mtg_sensu, GOC:pr]
EOG8K9DSN	GO:0043065	1/92	positive regulation of apoptotic process	biological_process	"Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process." [GOC:jl, GOC:mtg_apoptosis]
EOG8K9DSN	GO:0007468	1/92	regulation of rhodopsin gene expression	biological_process	"Any process that modulates the frequency, rate or extent of rhodopsin gene expression. This includes transcriptional, translational, or posttranslational regulation." [GOC:dph, GOC:go_curators, GOC:tb]
EOG8K9DSN	GO:0048813	1/92	dendrite morphogenesis	biological_process	"The process in which the anatomical structures of a dendrite are generated and organized. A dendrite is a freely branching protoplasmic process of a nerve cell." [GOC:jl, ISBN:0198506732]
EOG8K9DSN	GO:0008258	1/92	head involution	biological_process	"Movement of the anterior ectoderm to the interior of the embryo." [ISBN:08795694238]
EOG8K9DSN	GO:0007561	1/92	imaginal disc eversion	biological_process	"The eversion (turning inside out) of imaginal discs from their peripodial sacs, resulting in movement of the epithelium to the outside of the larval epidermis." [PMID:11494317]
EOG8K9DSN	GO:0008231	1/92	repressor ecdysone receptor complex	cellular_component	"A protein complex consisting of a heterodimer of Ecdysone receptor (EcR) and ultraspiracle (usp) plus an associated corepressor such as SMRTER, which represses transcription of target genes." [PMID:10488333]
EOG8K9DSN	GO:0007286	1/92	spermatid development	biological_process	"The process whose specific outcome is the progression of a spermatid over time, from its formation to the mature structure." [GOC:dph, GOC:go_curators]
EOG8K9DSN	GO:0042220	1/92	response to cocaine	biological_process	"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cocaine stimulus. Cocaine is a crystalline alkaloid obtained from the leaves of the coca plant." [CHEBI:27958, GOC:ef, GOC:jl]
EOG8K9DSN	GO:0007443	1/92	Malpighian tubule morphogenesis	biological_process	"The process in which the anatomical structures of the Malpighian tubule are generated and organized. This process takes place entirely during the embryonic phase. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which leads into the posterior part of the gut." [GOC:bf, ISBN:0582227089]
EOG8K9DSN	GO:0008544	1/92	epidermis development	biological_process	"The process whose specific outcome is the progression of the epidermis over time, from its formation to the mature structure. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species." [GOC:go_curators, UBERON:0001003]
EOG8K9DSN	GO:0045938	1/92	positive regulation of circadian sleep/wake cycle, sleep	biological_process	"Any process that activates or increases the duration or quality of sleep, a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals." [GOC:go_curators]
EOG8K9DSN	GO:0040034	1/92	regulation of development, heterochronic	biological_process	"Any process that modulates the consistent predetermined time point at which an integrated living unit or organism progresses from an initial condition to a later condition and the rate at which this time point is reached." [PMID:9442909]
EOG8K9DSN	GO:0007281	1/92	germ cell development	biological_process	"The process whose specific outcome is the progression of an immature germ cell over time, from its formation to the mature structure (gamete). A germ cell is any reproductive cell in a multicellular organism." [GOC:go_curators]
EOG8K9DSN	GO:0048666	1/92	neuron development	biological_process	"The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." [GOC:dph]
EOG8K9DSN	GO:0003677	1/92	DNA binding	molecular_function	"Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid)." [GOC:dph, GOC:jl, GOC:tb, GOC:vw]
EOG8K9DSN	GO:0046982	1/92	protein heterodimerization activity	molecular_function	"Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer." [GOC:ai]
EOG8K9DSN	GO:0007422	1/92	peripheral nervous system development	biological_process	"The process whose specific outcome is the progression of the peripheral nervous system over time, from its formation to the mature structure. The peripheral nervous system is one of the two major divisions of the nervous system. Nerves in the PNS connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands." [GOC:go_curators, UBERON:0000010]
EOG8K9DSN	GO:0008230	1/92	ecdysone receptor holocomplex	cellular_component	"A heterodimeric complex containing the products of the insect genes Ecdysone receptor (EcR) and ultraspiracle (usp). Binding of ecdysone promotes association between the two subunits, and the receptor complex then initiates molting and metamorphosis by binding DNA and regulating the transcription of target genes." [GOC:bf, PMID:14592980]
EOG8K9DSN	GO:0006357	1/92	regulation of transcription from RNA polymerase II promoter	biological_process	"Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:go_curators, GOC:txnOH]
EOG8K9DSN	GO:0035075	1/92	response to ecdysone	biological_process	"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ecdysone stimulus." [GOC:bf]
EOG8K9DSN	GO:0016319	1/92	mushroom body development	biological_process	"The process whose specific outcome is the progression of the mushroom body over time, from its formation to the mature structure. The mushroom body is composed of the prominent neuropil structures of the insect central brain, thought to be crucial for olfactory associated learning. These consist mainly of a bulbous calyx and tightly packaged arrays of thin parallel fibers of the Kenyon cells." [PMID:8790424]
EOG8K9DSN	GO:0008232	1/92	activator ecdysone receptor complex	cellular_component	"A protein complex consisting of a heterodimer of Ecdysone receptor (EcR) and ultraspiracle (usp) bound to the ligand ecdysone, which activates transcription of target genes." [PMID:10488333]
EOG8K9DSN	GO:0048738	1/92	cardiac muscle tissue development	biological_process	"The process whose specific outcome is the progression of cardiac muscle over time, from its formation to the mature structure." [GOC:dph, GOC:jid, GOC:lm]
EOG8K9DSN	GO:0007476	1/92	imaginal disc-derived wing morphogenesis	biological_process	"The process in which the anatomical structures of the imaginal disc-derived wing are generated and organized. The wing is an appendage modified for flying." [GOC:bf, GOC:mtg_sensu]
EOG8K9DSN	GO:0016322	1/92	neuron remodeling	biological_process	"The developmentally regulated remodeling of neuronal projections such as pruning to eliminate the extra dendrites and axons projections set up in early stages of nervous system development." [GOC:hb]