EOG8KM1GX GO:0005524 26/99 ATP binding molecular_function "Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator." [ISBN:0198506732] EOG8KM1GX GO:0006298 26/99 mismatch repair biological_process "A system for the correction of errors in which an incorrect base, which cannot form hydrogen bonds with the corresponding base in the parent strand, is incorporated into the daughter strand. The mismatch repair system promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops and heterologies generated during DNA replication and recombination." [ISBN:0198506732, PMID:11687886] EOG8KM1GX GO:0030983 25/99 mismatched DNA binding molecular_function "Interacting selectively and non-covalently with double-stranded DNA containing one or more mismatches." [GOC:mah] EOG8KM1GX GO:0008094 1/99 DNA-dependent ATPase activity molecular_function "Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction requires the presence of single- or double-stranded DNA, and it drives another reaction." [EC:3.6.1.3, GOC:jl] EOG8KM1GX GO:0000400 1/99 four-way junction DNA binding molecular_function "Interacting selectively and non-covalently with DNA containing four-way junctions, also known as Holliday junctions, a structure where two DNA double strands are held together by reciprocal exchange of two of the four strands, one strand each from the two original helices." [GOC:krc, ISBN:0815332181, PMID:15563464] EOG8KM1GX GO:0032138 1/99 single base insertion or deletion binding molecular_function "Interacting selectively and non-covalently with double-stranded DNA containing a single base insertion or deletion." [GOC:vk] EOG8KM1GX GO:0000228 1/99 nuclear chromosome cellular_component "A chromosome that encodes the nuclear genome and is found in the nucleus of a eukaryotic cell during the cell cycle phases when the nucleus is intact." [GOC:dph, GOC:mah] EOG8KM1GX GO:0045910 1/99 negative regulation of DNA recombination biological_process "Any process that stops, prevents, or reduces the frequency, rate or extent of DNA recombination." [GOC:go_curators] EOG8KM1GX GO:0000710 1/99 meiotic mismatch repair biological_process "A system for the identification and correction of base-base mismatches, small insertion-deletion loops, and regions of heterology that are present in duplex DNA formed with strands from two recombining molecules. Correction of the mismatch can result in non-Mendelian segregation of alleles following meiosis." [GOC:elh, PMID:10357855] EOG8KM1GX GO:0008630 1/99 intrinsic apoptotic signaling pathway in response to DNA damage biological_process "A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the detection of DNA damage, and ends when the execution phase of apoptosis is triggered." [GOC:go_curators, GOC:mtg_apoptosis] EOG8KM1GX GO:0007131 1/99 reciprocal meiotic recombination biological_process "The cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate. This results in the equal exchange of genetic material between non-sister chromatids in a pair of homologous chromosomes. These reciprocal recombinant products ensure the proper segregation of homologous chromosomes during meiosis I and create genetic diversity." [PMID:2087779] EOG8KM1GX GO:0006200 1/99 obsolete ATP catabolic process biological_process "OBSOLETE. The chemical reactions and pathways resulting in the breakdown of ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator." [GOC:ai] EOG8KM1GX GO:0006281 1/99 DNA repair biological_process "The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway." [PMID:11563486] EOG8KM1GX GO:0003684 1/99 damaged DNA binding molecular_function "Interacting selectively and non-covalently with damaged DNA." [GOC:jl] EOG8KM1GX GO:0009411 1/99 response to UV biological_process "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers." [GOC:hb] EOG8KM1GX GO:0043570 1/99 maintenance of DNA repeat elements biological_process "Any process involved in sustaining the fidelity and copy number of DNA repeat elements." [GOC:jl] EOG8KM1GX GO:0032301 1/99 MutSalpha complex cellular_component "A heterodimer involved in the recognition and repair of base-base and small insertion/deletion mismatches. In human the complex consists of two subunits, MSH2 and MSH6." [PMID:11005803] EOG8KM1GX GO:0032137 1/99 guanine/thymine mispair binding molecular_function "Interacting selectively and non-covalently with double-stranded DNA containing a G/T mispair." [GOC:vk]