EOG8Q5C48 GO:0004725 25/89 protein tyrosine phosphatase activity molecular_function "Catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate." [EC:3.1.3.48] EOG8Q5C48 GO:0005737 1/89 cytoplasm cellular_component "All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures." [ISBN:0198547684] EOG8Q5C48 GO:0048471 1/89 perinuclear region of cytoplasm cellular_component "Cytoplasm situated near, or occurring around, the nucleus." [GOC:jid] EOG8Q5C48 GO:0071456 1/89 cellular response to hypoxia biological_process "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level." [GOC:mah] EOG8Q5C48 GO:0007411 1/89 axon guidance biological_process "The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues." [ISBN:0878932437] EOG8Q5C48 GO:0046627 1/89 negative regulation of insulin receptor signaling pathway biological_process "Any process that stops, prevents, or reduces the frequency, rate or extent of insulin receptor signaling." [GOC:bf] EOG8Q5C48 GO:0006470 1/89 protein dephosphorylation biological_process "The process of removing one or more phosphoric residues from a protein." [GOC:hb] EOG8Q5C48 GO:0032880 1/89 regulation of protein localization biological_process "Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location." [GOC:dph, GOC:mah, GOC:tb] EOG8Q5C48 GO:0008285 1/89 negative regulation of cell proliferation biological_process "Any process that stops, prevents or reduces the rate or extent of cell proliferation." [GOC:go_curators] EOG8Q5C48 GO:0005740 1/89 mitochondrial envelope cellular_component "The double lipid bilayer enclosing the mitochondrion and separating its contents from the cell cytoplasm; includes the intermembrane space." [GOC:ai, GOC:pz] EOG8Q5C48 GO:0016020 1/89 membrane cellular_component "A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it." [GOC:dos, GOC:mah, ISBN:0815316194] EOG8Q5C48 GO:0012505 1/89 endomembrane system cellular_component "A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles." [GOC:lh] EOG8Q5C48 GO:0046426 1/89 negative regulation of JAK-STAT cascade biological_process "Any process that stops, prevents, or reduces the frequency, rate or extent of the JAK-STAT signaling pathway activity." [GOC:bf] EOG8Q5C48 GO:0005515 1/89 protein binding molecular_function "Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules)." [GOC:go_curators] EOG8Q5C48 GO:0005634 1/89 nucleus cellular_component "A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent." [GOC:go_curators] EOG8Q5C48 GO:0050732 1/89 negative regulation of peptidyl-tyrosine phosphorylation biological_process "Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine." [GOC:ai] EOG8Q5C48 GO:0000278 1/89 mitotic cell cycle biological_process "Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent." [GOC:mah, ISBN:0815316194, Reactome:69278] EOG8Q5C48 GO:0050254 1/89 rhodopsin kinase activity molecular_function "Catalysis of the reaction: ATP + rhodopsin = ADP + phosphorhodopsin." [EC:2.7.11.14, MetaCyc:RHODOPSIN-KINASE-RXN] EOG8Q5C48 GO:0031647 1/89 regulation of protein stability biological_process "Any process that affects the structure and integrity of a protein, altering the likelihood of its degradation or aggregation." [GOC:dph, GOC:mah, GOC:tb] EOG8Q5C48 GO:0035335 1/89 peptidyl-tyrosine dephosphorylation biological_process "The removal of phosphoric residues from peptidyl-O-phospho-tyrosine to form peptidyl-tyrosine." [GOC:bf] EOG8Q5C48 GO:0007377 1/89 germ-band extension biological_process "Elongation of the germ band on the ventral side of the embryo, accompanied by a halving in width. The elongation process pushes the posterior midgut invagination closed and compresses the amnioserosa further." [ISBN:08795694238]