EOG8Q87BD GO:0048015 33/104 phosphatidylinositol-mediated signaling biological_process "A series of molecular signals in which a cell uses a phosphatidylinositol-mediated signaling to convert a signal into a response. Phosphatidylinositols include phosphatidylinositol (PtdIns) and its phosphorylated derivatives." [GOC:bf, GOC:ceb, ISBN:0198506732] EOG8Q87BD GO:0046854 30/104 phosphatidylinositol phosphorylation biological_process "The process of introducing one or more phosphate groups into a phosphatidylinositol, any glycerophosphoinositol having one phosphatidyl group esterified to one of the hydroxy groups of inositol." [ISBN:0198506732] EOG8Q87BD GO:0005524 29/104 ATP binding molecular_function "Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator." [ISBN:0198506732] EOG8Q87BD GO:0016773 28/104 phosphotransferase activity, alcohol group as acceptor molecular_function "Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to an alcohol group (acceptor)." [GOC:jl] EOG8Q87BD GO:0016301 27/104 kinase activity molecular_function "Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule." [ISBN:0198506732] EOG8Q87BD GO:0046934 4/104 phosphatidylinositol-4,5-bisphosphate 3-kinase activity molecular_function "Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + ATP = a 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate + ADP + 2 H(+)." [EC:2.7.1.153, RHEA:21295] EOG8Q87BD GO:0016021 1/104 integral component of membrane cellular_component "The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:dos, GOC:go_curators] EOG8Q87BD GO:0048813 1/104 dendrite morphogenesis biological_process "The process in which the anatomical structures of a dendrite are generated and organized. A dendrite is a freely branching protoplasmic process of a nerve cell." [GOC:jl, ISBN:0198506732] EOG8Q87BD GO:0001727 1/104 lipid kinase activity molecular_function "Catalysis of the phosphorylation of a simple or complex lipid." [GOC:hjd] EOG8Q87BD GO:0042127 1/104 regulation of cell proliferation biological_process "Any process that modulates the frequency, rate or extent of cell proliferation." [GOC:jl] EOG8Q87BD GO:0006979 1/104 response to oxidative stress biological_process "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals." [GOC:jl, PMID:12115731] EOG8Q87BD GO:0048477 1/104 oogenesis biological_process "The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster." [GOC:kmv, GOC:mtg_sensu, GOC:pr] EOG8Q87BD GO:0060074 1/104 synapse maturation biological_process "The process that organizes a synapse so that it attains its fully functional state. Synaptic maturation plays a critical role in the establishment of effective synaptic connections in early development." [GOC:dph, GOC:ef] EOG8Q87BD GO:0008286 1/104 insulin receptor signaling pathway biological_process "The series of molecular signals generated as a consequence of the insulin receptor binding to insulin." [GOC:ceb] EOG8Q87BD GO:0036092 1/104 phosphatidylinositol-3-phosphate biosynthetic process biological_process "The chemical reactions and pathways resulting in the formation of phosphatidylinositol-3-phosphate, a phosphatidylinositol monophosphate carrying the phosphate group at the 3-position." [CHEBI:26034, GOC:al, GOC:vw] EOG8Q87BD GO:0045572 1/104 positive regulation of imaginal disc growth biological_process "Any process that activates or increases the frequency, rate or extent of imaginal disc growth." [GOC:go_curators] EOG8Q87BD GO:0040014 1/104 regulation of multicellular organism growth biological_process "Any process that modulates the frequency, rate or extent of growth of the body of an organism so that it reaches its usual body size." [GOC:dph, GOC:ems, GOC:tb] EOG8Q87BD GO:0017124 1/104 SH3 domain binding molecular_function "Interacting selectively and non-covalently with a SH3 domain (Src homology 3) of a protein, small protein modules containing approximately 50 amino acid residues found in a great variety of intracellular or membrane-associated proteins." [GOC:go_curators, Pfam:PF00018] EOG8Q87BD GO:0055115 1/104 entry into diapause biological_process "The dormancy process that results in entry into diapause. Diapause is a neurohormonally mediated, dynamic state of low metabolic activity. Associated characteristics of this form of dormancy include reduced morphogenesis, increased resistance to environmental extremes, and altered or reduced behavioral activity. Full expression develops in a species-specific manner, usually in response to a number of environmental stimuli that precede unfavorable conditions. Once diapause has begun, metabolic activity is suppressed even if conditions favorable for development prevail. Once initiated, only certain stimuli are capable of releasing the organism from this state, and this characteristic is essential in distinguishing diapause from hibernation." [GOC:ds, GOC:jid, GOC:mah] EOG8Q87BD GO:0007552 1/104 metamorphosis biological_process "A biological process in which an animal physically develops after birth or hatching, involving a conspicuous and relatively abrupt change in the animal's form or structure. Examples include the change from tadpole to frog, and the change from larva to adult. An example of this is found in Drosophila melanogaster." [GOC:sensu, ISBN:0198506732, ISBN:0721662544] EOG8Q87BD GO:0002168 1/104 instar larval development biological_process "The process whose specific outcome is the progression of the larva over time, from its formation to the mature structure. This begins with the newly hatched first-instar larva, through its maturation to the end of the last larval stage. An example of this process is found in Drosophila melanogaster." [GOC:bf, GOC:mtg_sensu] EOG8Q87BD GO:0022857 1/104 transmembrane transporter activity molecular_function "Enables the transfer of a substance from one side of a membrane to the other." [GOC:mtg_transport, ISBN:0815340729] EOG8Q87BD GO:0048169 1/104 regulation of long-term neuronal synaptic plasticity biological_process "A process that modulates long-term neuronal synaptic plasticity, the ability of neuronal synapses to change long-term as circumstances require. Long-term neuronal synaptic plasticity generally involves increase or decrease in actual synapse numbers." [GOC:jid, http://www.mercksource.com, PMID:11891290] EOG8Q87BD GO:0006914 1/104 autophagy biological_process "The process in which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation." [GOC:autophagy, ISBN:0198547684, PMID:11099404, PMID:9412464] EOG8Q87BD GO:2000377 1/104 regulation of reactive oxygen species metabolic process biological_process "Any process that modulates the frequency, rate or extent of reactive oxygen species metabolic process." [GOC:mah] EOG8Q87BD GO:0051823 1/104 regulation of synapse structural plasticity biological_process "Any process that modulates the frequency, rate or extent of synapse structural plasticity. Synapse structural plasticity is a type of cytoskeletal remodeling; this remodeling is induced by stimuli that can lead to long term potentiation and it can be activity-dependent or -independent. Examples of cytoskeletal changes include the formation of new spines and increase in spine size; this can be accompanied by the insertion of greater numbers of glutamate (or other neurotransmitter) receptors into the post-synaptic membrane." [PMID:11063967, PMID:14976517, PMID:9884123] EOG8Q87BD GO:0045793 1/104 positive regulation of cell size biological_process "Any process that increases cell size." [GOC:go_curators] EOG8Q87BD GO:0035005 1/104 1-phosphatidylinositol-4-phosphate 3-kinase activity molecular_function "Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4-phosphate + ATP = 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + ADP + 2 H(+)." [EC:2.7.1.154, RHEA:18376] EOG8Q87BD GO:0050773 1/104 regulation of dendrite development biological_process "Any process that modulates the frequency, rate or extent of dendrite development." [GOC:ai] EOG8Q87BD GO:0046620 1/104 regulation of organ growth biological_process "Any process that modulates the frequency, rate or extent of growth of an organ of an organism." [GOC:bf, GOC:tb] EOG8Q87BD GO:0010507 1/104 negative regulation of autophagy biological_process "Any process that stops, prevents, or reduces the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm." [GOC:dph, GOC:tb] EOG8Q87BD GO:0030536 1/104 larval feeding behavior biological_process "Feeding behavior in a larval (immature) organism." [GOC:mah] EOG8Q87BD GO:0030307 1/104 positive regulation of cell growth biological_process "Any process that activates or increases the frequency, rate, extent or direction of cell growth." [GOC:go_curators] EOG8Q87BD GO:0007390 1/104 germ-band shortening biological_process "The spreading of the amnioserosa from its compressed state to cover the whole of the dorsal surface. Initiating in the thorax and spreading posteriorly, it is accompanied by the transition from a parasegmental to segmental division of the embryo." [GOC:bf, PMID:12147138] EOG8Q87BD GO:0016772 1/104 transferase activity, transferring phosphorus-containing groups molecular_function "Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor)." [GOC:jl, ISBN:0198506732] EOG8Q87BD GO:0005886 1/104 plasma membrane cellular_component "The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins." [ISBN:0716731363] EOG8Q87BD GO:0046622 1/104 positive regulation of organ growth biological_process "Any process that activates or increases the frequency, rate or extent of growth of an organ of an organism." [GOC:bf, GOC:tb] EOG8Q87BD GO:0016310 1/104 phosphorylation biological_process "The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide." [ISBN:0198506732] EOG8Q87BD GO:0008361 1/104 regulation of cell size biological_process "Any process that modulates the size of a cell." [GOC:go_curators] EOG8Q87BD GO:0051124 1/104 synaptic growth at neuromuscular junction biological_process "The growth of a synapse at a neuromuscular junction, the site of apposition of a motor end plate and the subneural cleft of the skeletal muscle fiber that it innervates." [ISBN:0721662544] EOG8Q87BD GO:0007436 1/104 larval salivary gland morphogenesis biological_process "The process, occurring in the larva, by which the anatomical structures of the salivary gland are generated and organized." [GOC:jid] EOG8Q87BD GO:0005829 1/104 cytosol cellular_component "The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes." [GOC:hjd, GOC:jl] EOG8Q87BD GO:0045927 1/104 positive regulation of growth biological_process "Any process that activates or increases the rate or extent of growth, the increase in size or mass of all or part of an organism." [GOC:go_curators] EOG8Q87BD GO:0002164 1/104 larval development biological_process "The process whose specific outcome is the progression of the larva over time, from its formation to the mature structure. The larva is the early, immature form of an that at birth or hatching is fundamentally unlike its parent and must metamorphose before assuming the adult characters." [GOC:jid, ISBN:0877795088] EOG8Q87BD GO:0016322 1/104 neuron remodeling biological_process "The developmentally regulated remodeling of neuronal projections such as pruning to eliminate the extra dendrites and axons projections set up in early stages of nervous system development." [GOC:hb] EOG8Q87BD GO:0045727 1/104 positive regulation of translation biological_process "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA." [GOC:dph, GOC:go_curators, GOC:tb] EOG8Q87BD GO:0016303 1/104 1-phosphatidylinositol-3-kinase activity molecular_function "Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + ATP = a 1-phosphatidyl-1D-myo-inositol 3-phosphate + ADP + 2 H(+)." [EC:2.7.1.137, RHEA:12712] EOG8Q87BD GO:0042059 1/104 negative regulation of epidermal growth factor receptor signaling pathway biological_process "Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity." [GOC:go_curators] EOG8Q87BD GO:0009267 1/104 cellular response to starvation biological_process "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment." [GOC:jl] EOG8Q87BD GO:0016049 1/104 cell growth biological_process "The process in which a cell irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present." [GOC:ai] EOG8Q87BD GO:0005943 1/104 phosphatidylinositol 3-kinase complex, class IA cellular_component "A class I phosphatidylinositol 3-kinase complex that possesses 1-phosphatidylinositol-4-phosphate 3-kinase activity; comprises a catalytic class IA phosphoinositide 3-kinase (PI3K) subunit and an associated SH2 domain-containing regulatory subunit that is a member of a family of related proteins often called p85 proteins. Through the interaction with the SH2-containing adaptor subunits, Class IA PI3K catalytic subunits are linked to tyrosine kinase signaling pathways." [PMID:9255069, PMID:9759495]