EOG8SFCM0 GO:0005765 1/89 lysosomal membrane cellular_component "The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm." [GOC:ai] EOG8SFCM0 GO:0031902 1/89 late endosome membrane cellular_component "The lipid bilayer surrounding a late endosome." [GOC:pz] EOG8SFCM0 GO:0050797 1/89 thymidylate synthase (FAD) activity molecular_function "Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dUMP + NADPH + H+ = dTMP + tetrahydrofolate + NADP+." [EC:2.1.1.148] EOG8SFCM0 GO:0035280 1/89 miRNA loading onto RISC involved in gene silencing by miRNA biological_process "The transfer of a microRNA (miRNA) strand from a miRNA:miRNA duplex onto the RNA-initiated silencing complex (RISC)." [PMID:14744438] EOG8SFCM0 GO:0031085 1/89 BLOC-3 complex cellular_component "A protein complex required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules. The human complex contains the Hps1 and Hps4 proteins." [PMID:12756248] EOG8SFCM0 GO:0070923 1/89 siRNA loading onto RISC involved in chromatin silencing by small RNA biological_process "The process in which a single-stranded small RNA associates with the RNA-initiated silencing complex (RISC); occurs as part of a process of chromatin silencing by small RNA." [GOC:mah, PMID:19239886] EOG8SFCM0 GO:0060967 1/89 negative regulation of gene silencing by RNA biological_process "Any process that decreases the rate, frequency, or extent of gene silencing by RNA. Gene silencing by RNA is the process in which RNA molecules inactivate expression of target genes." [GOC:dph, GOC:tb]