EOG8VHNMN GO:0005524 22/90 ATP binding molecular_function "Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator." [ISBN:0198506732] EOG8VHNMN GO:0051013 17/90 microtubule severing biological_process "The process in which a microtubule is broken down into smaller segments." [GOC:ai, PMID:14657234] EOG8VHNMN GO:0005874 17/90 microtubule cellular_component "Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle." [ISBN:0879693568] EOG8VHNMN GO:0031117 17/90 positive regulation of microtubule depolymerization biological_process "Any process that activates or increases the frequency, rate or extent of microtubule depolymerization." [GOC:mah] EOG8VHNMN GO:0034214 17/90 protein hexamerization biological_process "The formation of a protein hexamer, a macromolecular structure consisting of six noncovalently associated identical or nonidentical subunits." [GOC:ecd] EOG8VHNMN GO:0005737 17/90 cytoplasm cellular_component "All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures." [ISBN:0198547684] EOG8VHNMN GO:0005634 17/90 nucleus cellular_component "A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent." [GOC:go_curators] EOG8VHNMN GO:0016021 17/90 integral component of membrane cellular_component "The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:dos, GOC:go_curators] EOG8VHNMN GO:0008568 17/90 microtubule-severing ATPase activity molecular_function "Catalysis of the reaction: ATP + H2O = ADP + phosphate. Catalysis of the severing of a microtubule at a specific spot along its length, coupled to the hydrolysis of ATP." [EC:3.6.4.3, PMID:10910766] EOG8VHNMN GO:0006200 14/90 obsolete ATP catabolic process biological_process "OBSOLETE. The chemical reactions and pathways resulting in the breakdown of ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator." [GOC:ai] EOG8VHNMN GO:0008017 14/90 microtubule binding molecular_function "Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers." [GOC:krc] EOG8VHNMN GO:0005694 12/90 chromosome cellular_component "A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information." [ISBN:0198547684] EOG8VHNMN GO:0005819 12/90 spindle cellular_component "The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart." [ISBN:0198547684] EOG8VHNMN GO:0030154 12/90 cell differentiation biological_process "The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state." [ISBN:0198506732] EOG8VHNMN GO:0007079 12/90 mitotic chromosome movement towards spindle pole biological_process "The cell cycle process in which the directed movement of chromosomes from the center of the spindle towards the spindle poles occurs. This mediates by the shortening of microtubules attached to the chromosomes, during mitosis." [GOC:ai] EOG8VHNMN GO:0000022 12/90 mitotic spindle elongation biological_process "The cell cycle process in which the distance is lengthened between poles of the spindle. Spindle elongation begins during prophase and ends during anaphase B." [GOC:mtg_cell_cycle, GOC:vw] EOG8VHNMN GO:0008344 12/90 adult locomotory behavior biological_process "Locomotory behavior in a fully developed and mature organism." [GOC:ai] EOG8VHNMN GO:0016887 12/90 ATPase activity molecular_function "Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction." [EC:3.6.1.3, GOC:jl] EOG8VHNMN GO:0007399 12/90 nervous system development biological_process "The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state." [GOC:dgh] EOG8VHNMN GO:0005813 12/90 centrosome cellular_component "A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle." [GOC:mah, ISBN:0198547684] EOG8VHNMN GO:0050803 11/90 regulation of synapse structure or activity biological_process "Any process that modulates the physical form or the activity of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell)." [GOC:ai] EOG8VHNMN GO:0005815 5/90 microtubule organizing center cellular_component "An intracellular structure that can catalyze gamma-tubulin-dependent microtubule nucleation and that can anchor microtubules by interacting with their minus ends, plus ends or sides." [GOC:vw, http://en.wikipedia.org/wiki/Microtubule_organizing_center, ISBN:0815316194, PMID:17072892, PMID:17245416] EOG8VHNMN GO:0017111 5/90 nucleoside-triphosphatase activity molecular_function "Catalysis of the reaction: a nucleoside triphosphate + H2O = nucleoside diphosphate + phosphate." [EC:3.6.1.15] EOG8VHNMN GO:0043195 1/90 terminal bouton cellular_component "Terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it." [GOC:dph, GOC:mc, GOC:nln, PMID:10218156, PMID:8409967] EOG8VHNMN GO:0007626 1/90 locomotory behavior biological_process "The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions." [GOC:dph] EOG8VHNMN GO:0005515 1/90 protein binding molecular_function "Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules)." [GOC:go_curators] EOG8VHNMN GO:1900075 1/90 positive regulation of neuromuscular synaptic transmission biological_process "Any process that activates or increases the frequency, rate or extent of neuromuscular synaptic transmission." [GOC:kmv, GOC:TermGenie] EOG8VHNMN GO:2000331 1/90 regulation of terminal button organization biological_process "Any process that modulates the frequency, rate or extent of terminal button organization." [GOC:BHF, GOC:mah] EOG8VHNMN GO:0000502 1/90 proteasome complex cellular_component "A large multisubunit complex which catalyzes protein degradation, found in eukaryotes, archaea and some bacteria. In eukaryotes, this complex consists of the barrel shaped proteasome core complex and one or two associated proteins or complexes that act in regulating entry into or exit from the core." [GOC:rb, http://en.wikipedia.org/wiki/Proteasome] EOG8VHNMN GO:0035099 1/90 hemocyte migration biological_process "The directed movement of a hemocyte within the embryo. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. In Drosophila, embryonic hemocytes originate from the head mesoderm as a cluster of cells. The cluster splits into two and one group of cells crosses the amnioserosa. Both populations then spread toward the middle of the embryo and then disperse evenly throughout the embryo." [GOC:bf, GOC:mtg_sensu, PMID:12885551] EOG8VHNMN GO:0045886 1/90 negative regulation of synaptic growth at neuromuscular junction biological_process "Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic growth at neuromuscular junction." [GOC:go_curators] EOG8VHNMN GO:0043014 1/90 alpha-tubulin binding molecular_function "Interacting selectively and non-covalently with the microtubule constituent protein alpha-tubulin." [GOC:jl] EOG8VHNMN GO:0000226 1/90 microtubule cytoskeleton organization biological_process "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins." [GOC:mah] EOG8VHNMN GO:1900074 1/90 negative regulation of neuromuscular synaptic transmission biological_process "Any process that stops, prevents or reduces the frequency, rate or extent of neuromuscular synaptic transmission." [GOC:kmv, GOC:TermGenie] EOG8VHNMN GO:0000070 1/90 mitotic sister chromatid segregation biological_process "The cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets." [GOC:ai, GOC:jl] EOG8VHNMN GO:0045887 1/90 positive regulation of synaptic growth at neuromuscular junction biological_process "Any process that activates or increases the frequency, rate or extent of synaptic growth at neuromuscular junction." [GOC:go_curators] EOG8VHNMN GO:0036078 1/90 minus-end specific microtubule depolymerization biological_process "The removal of tubulin heterodimers from the minus end of a microtubule." [GOC:sart, PMID:17452528] EOG8VHNMN GO:0031594 1/90 neuromuscular junction cellular_component "The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential." [GOC:nln]