EOG8VQD4W GO:0015934 25/162 large ribosomal subunit cellular_component "The larger of the two subunits of a ribosome. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site)." [ISBN:0198506732] EOG8VQD4W GO:0003735 25/162 structural constituent of ribosome molecular_function "The action of a molecule that contributes to the structural integrity of the ribosome." [GOC:mah] EOG8VQD4W GO:0006412 25/162 translation biological_process "The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA. Translation ends with the release of a polypeptide chain from the ribosome." [GOC:go_curators] EOG8VQD4W GO:0070403 23/162 NAD+ binding molecular_function "Interacting selectively and non-covalently with the oxidized form, NAD, of nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions." [GOC:mah] EOG8VQD4W GO:0051298 1/162 centrosome duplication biological_process "The replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized." [GOC:ai] EOG8VQD4W GO:0046872 1/162 metal ion binding molecular_function "Interacting selectively and non-covalently with any metal ion." [GOC:ai] EOG8VQD4W GO:0016787 1/162 hydrolase activity molecular_function "Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3." [ISBN:0198506732] EOG8VQD4W GO:0000022 1/162 mitotic spindle elongation biological_process "The cell cycle process in which the distance is lengthened between poles of the spindle. Spindle elongation begins during prophase and ends during anaphase B." [GOC:mtg_cell_cycle, GOC:vw] EOG8VQD4W GO:0007052 1/162 mitotic spindle organization biological_process "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle." [GOC:mah] EOG8VQD4W GO:0008340 1/162 determination of adult lifespan biological_process "The control of viability and duration in the adult phase of the life-cycle." [GOC:ems]