EOG8W9MKG GO:0018024 23/105 histone-lysine N-methyltransferase activity molecular_function "Catalysis of the reaction: S-adenosyl-L-methionine + histone L-lysine = S-adenosyl-L-homocysteine + histone N6-methyl-L-lysine. The methylation of peptidyl-lysine in histones forms N6-methyl-L-lysine, N6,N6-dimethyl-L-lysine and N6,N6,N6-trimethyl-L-lysine derivatives." [EC:2.1.1.43, RESID:AA0074, RESID:AA0075, RESID:AA0076] EOG8W9MKG GO:0042799 2/105 histone methyltransferase activity (H4-K20 specific) molecular_function "Catalysis of the reaction: S-adenosyl-L-methionine + histone H4 L-lysine (position 20) = S-adenosyl-L-homocysteine + histone H4 N6-methyl-L-lysine (position 20). This reaction is the addition of a methyl group onto lysine at position 20 of the histone H4 protein." [PMID:12086618] EOG8W9MKG GO:0016571 2/105 histone methylation biological_process "The modification of histones by addition of methyl groups." [GOC:ai] EOG8W9MKG GO:0006355 2/105 regulation of transcription, DNA-templated biological_process "Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription." [GOC:go_curators, GOC:txnOH] EOG8W9MKG GO:0007067 2/105 mitotic nuclear division biological_process "A cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell." [GOC:dph, GOC:ma, GOC:mah, ISBN:0198547684] EOG8W9MKG GO:0005634 2/105 nucleus cellular_component "A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent." [GOC:go_curators] EOG8W9MKG GO:0006351 2/105 transcription, DNA-templated biological_process "The cellular synthesis of RNA on a template of DNA." [GOC:jl, GOC:txnOH] EOG8W9MKG GO:0005700 2/105 polytene chromosome cellular_component "A type of chromosome in a polyploid cell, formed when multiple copies of homologous chromosomes are aligned side by side to give a giant chromosome in which distinct chromosome bands are readily visible." [ISBN:0198506732] EOG8W9MKG GO:0030261 1/105 chromosome condensation biological_process "The progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells." [GOC:mah, ISBN:0815316194] EOG8W9MKG GO:0034771 1/105 histone H4-K20 monomethylation biological_process "The modification of histone H4 by addition of one methyl group to lysine at position 20 of the histone." [GOC:mah] EOG8W9MKG GO:0034770 1/105 histone H4-K20 methylation biological_process "The modification of histone H4 by addition of one or more methyl groups to lysine at position 20 of the histone." [GOC:mah] EOG8W9MKG GO:0000077 1/105 DNA damage checkpoint biological_process "A cell cycle checkpoint that regulates progression through the cell cycle in response to DNA damage. A DNA damage checkpoint may blocks cell cycle progression (in G1, G2 or metaphase) or slow the rate at which S phase proceeds." [GOC:mtg_cell_cycle]