EOG8ZPHB9 GO:0005634 1/4 nucleus cellular_component "A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent." [GOC:go_curators] EOG8ZPHB9 GO:0006355 1/4 regulation of transcription, DNA-templated biological_process "Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription." [GOC:go_curators, GOC:txnOH] EOG8ZPHB9 GO:0008270 1/4 zinc ion binding molecular_function "Interacting selectively and non-covalently with zinc (Zn) ions." [GOC:ai] EOG8ZPHB9 GO:0003712 1/4 transcription cofactor activity molecular_function "Interacting selectively and non-covalently with a regulatory transcription factor and also with the basal transcription machinery in order to modulate transcription. Cofactors generally do not bind the template nucleic acid, but rather mediate protein-protein interactions between regulatory transcription factors and the basal transcription machinery." [GOC:txnOH, PMID:10213677, PMID:16858867] EOG8ZPHB9 GO:0004402 1/4 histone acetyltransferase activity molecular_function "Catalysis of the reaction: acetyl-CoA + histone = CoA + acetyl-histone." [EC:2.3.1.48]